Effect of a gut commensal Lactobacillus strain Limosilactobacillus caviae JL20 on leptospiral whole-cell inactivated vaccine in hamsters.
- 2026-02-03
- PLoS neglected tropical diseases 20(2)
- Shilei Zhang
- Lianjie Ma
- Qi Cao
- Meijing Zhang
- Guixin Yan
- Wanqi Jiang
- Xufeng Xie
- Wenlong Zhang
- Yongguo Cao
- PubMed: 41632794
- DOI: 10.1371/journal.pntd.0013951
- Low evidence
- Animal Study
JL20 enhances both vaccine efficacy and cross-protection. Oral JL20 significantly increased vaccine-induced cross-reactive binding antibody titers and total IgG antibody responses.
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes