Lactobacillus rhamnosus and Increased B Cell Activation

• Effect of a gut commensal Lactobacillus strain Limosilactobacillus caviae JL20 on leptospiral whole-cell inactivated vaccine in hamsters.

  • 2026-02-03
  • PLoS neglected tropical diseases 20(2)
  • • Shilei Zhang
    • Lianjie Ma
    • Qi Cao
    • Meijing Zhang
    • Guixin Yan
    • Wanqi Jiang
    • Xufeng Xie
    • Wenlong Zhang
    • Yongguo Cao

  • PubMed: 41632794
  • DOI: 10.1371/journal.pntd.0013951

  5 Insights on

  • Increased B Cell Activation

  • Low evidence
  • Animal Study

  JL20 enhanced the surface expression of key markers-including CD40, CD80, CD86, and MHC-II-on B cells.

  Effect

  Beneficial

  Effect size

  Moderate