Modulation of Behavioral, Biochemical, Immunomodulatory, and Transcriptional Profiles by the Strain Limosilactobacillus fermentum U-21 in Combined Model of Parkinson's Disease in Wistar Rats.
- 2025-12-31
- International journal of molecular sciences 27(1)
- Diana A Reznikova
- Olga B Bekker
- Alla V Stavrovskaya
- Dmitry N Voronkov
- Andrei A Gerasimov
- Anastasiia K Pavlova
- Ivan A Potapov
- Mikhail V Ivanov
- Veronika S Letvinova
- Maya V Odorskaya
- Dilara A Mavletova
- Aleksey A Vatlin
- Sergey N Illarioshkin
- Valery N Danilenko
- PubMed: 41516320
- DOI: 10.3390/ijms27010446
- Low evidence
- Rigorous Journal
- Animal Study
In LAC and LAC + LPS groups, LfU21 mitigated the rise in α-synuclein, the decline in bdnf expression, and behavioral deficits in the "Open Field" and "Rung ladder" tests, respectively.
- Effect
- Beneficial
- Effect size
- Moderate