Probiotic intake and mental health in healthy working adults: a systematic review and meta-analysis of randomized controlled trials.
- 2026-01-08
- Meta-Analysis · n = 350
- BMC psychology 14(1)
- Sihem Ben Fredj
- Hela Kechiche
- Asma Chouchen
- Imen Akkari
- Rim Ghammam
- Nawel Zammit
- Nour Douss
- Afef Skhiri
- Maher Maoua
- Jihen Maatoug
- Imed Harrabi
- Olfa El Maalel
- PubMed: 41501907
- DOI: 10.1186/s40359-025-03885-5
- High evidence
the probiotic interventions were associated with a statistically significant reduction in cortisol levels, a key biomarker of physiological stress (SMD = -0.26, 95% confidence interval [CI] [-0.45, -0.08], p = 0.005).
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes