Effect of Probiotics on Psychiatric Symptoms and Central Nervous System Functions in Human Health and Disease: A Systematic Review and Meta-Analysis.
- 2022-01-30
- Meta-Analysis
- Nutrients 14(3)
- Charlotte Le Morvan de Sequeira
- Charlotte Hengstberger
- Paul Enck
- Isabelle Mack
- PubMed: 35276981
- DOI: 10.3390/nu14030621
- High evidence
- Rigorous Journal
At quantitative level, depression and psychiatric distress improved slightly in the probiotic condition (depression: mean difference -0.37 (95% CI: -0.55, -0.20); p ≤ 0.0001).
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes