Lactobacillus rhamnosus and Reduced Hepatic Oxidative Stress

• Levilactobacillus brevis MG5311 Alleviates Ethanol-Induced Liver Injury by Suppressing Hepatic Oxidative Stress in C57BL/6 Mice.

  • 2022-12-15
  • Microorganisms 10(12)
  • • Hyunna Jung
    • Sohyeon You
    • Soo-Im Choi
    • Chang-Ho Kang
    • Gun-Hee Kim

  • PubMed: 36557739
  • DOI: 10.3390/microorganisms10122488

  5 Insights on

  • Reduced Hepatic Oxidative Stress

  • Low evidence

  L. brevis MG5311 also decreased malondialdehyde levels and increased glutathione peroxidase (GPx) activity in liver tissues... increased the protein expression of SIRT1, PPARα, SOD1, CAT, and GPx 1/2 in liver tissue, while inhibiting CYP2E1 and SREBP-1c.

  Effect

  Beneficial

  Effect size

  Moderate