Intrahepatic Cholestasis of Pregnancy Increases Inflammatory Susceptibility in Neonatal Offspring by Modulating Gut Microbiota.
- 2022-06-13
- Observational
- Frontiers in immunology 13
- Qiong-Xi Lin
- Wan-Wen Huang
- Wei Shen
- Xiao-Shi Deng
- Zi-Yu Tang
- Zhen-Hui Chen
- Wei Zhao
- Hong-Ying Fan
- PubMed: 35769469
- DOI: 10.3389/fimmu.2022.889646
- Low evidence
- Animal Study
Treatment with the probiotic Lactobacillus rhamnosus LRX01 that inhibits FXR expression in the ileum reduced susceptibility to LPS exposure in ICP offspring.
- Effect
- Beneficial
- Effect size
- Moderate