Lactobacillus rhamnosus and Reduced UVB-Induced Skin Cell Damage

• Isolation, characterization and anti-UVB irradiation activity of an extracellular polysaccharide produced by Lacticaseibacillus rhamnosus VHPriobi O17.

  • 2022-10
  • Heliyon 8(10)
  • • Shudong Peng
    • Chaoqun Guo
    • Songjie Wu
    • Zhi Duan

  • PubMed: 36299523
  • DOI: 10.1016/j.heliyon.2022.e11125

  4 Insights on

  • Reduced UVB-Induced Skin Cell Damage

  • Low evidence

  The EPS (OP-2) can effectively alleviate HaCaT cells apoptosis and overproduction of reactive oxygen species (ROS) induced by UVB... inhibited the release of pro-inflammatory cytokines (IL-1α, IL-6 and IL-8); and suppressed the phosphorylation cascade of JNK and p38 MAPK to reduce the expression level of active-caspase3, ultimately prevented cell apoptosis.

  Effect

  Beneficial

  Effect size

  Moderate