Across 3 studies, all reported beneficial small-sized effects on skin barrier function, with one reaching statistical significance. Evidence comes from two randomized controlled trials in healthy middle-aged women and children/adolescents with atopic dermatitis, and one review. No consistent dose or duration data were available.
Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive, but this may reflect publication bias. Many of the included studies did not reach statistical significance, suggesting the effect may be smaller than the beneficial direction implies. No dose or form data were reported, limiting practical application.
Cheek skin moisture and transepidermal water loss improved for both groups after the intervention.
The skin sebum content increased in both the live cell (p < 0.0001) and the dead cell group (p < 0.0001), suggesting potential improvements in skin barrier functions.
postbiotics were found to accelerate wound closure, stimulate collagen synthesis, and improve barrier integrity