Effect of a bioactive product SEL001 from Lactobacillus sakei probio65 on gut microbiota and its anti-colitis effects in a TNBS-induced colitis mouse model
- 2020-01
- Clinical Trial
- Saudi Journal of Biological Sciences 27(1)
- I. Rather
- V. Bajpai
- Lew L. Ching
- R. Majumder
- Gyeong-Jun Nam
- N. Indugu
- Prashant Singh
- Sanjay Kumar
- N. Hajrah
- J. Sabir
- M. Kamli
- Yong-Ha Park
- PubMed: 31889846
- DOI: 10.1016/j.sjbs.2019.09.004
- Low evidence
- Animal Study
SEL001 significantly lowered pro-inflammatory cytokines, including CD4, TNF-α, and interleukin-6... SEL001 was effective and potent in reducing the inflammatory signatures of UC to a similar extent as did by the standard drug mesalamine (5-ASA).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes