Lactobacillus salivarius CRL 1328 and Reduced Inflammatory Response

• In vitro modulation of proinflammatory and proteolytic activities of Porphyromonas gingivalis by selected lactobacilli.

  • 2025-02-25
  • Journal of oral microbiology 17(1)
  • • Johana R Naja
    • Leyla Desparois
    • Elvira M Hebert
    • Maria Elena Fátima Nader
    • Lucila Saavedra
    • Carlos J Minahk
    • Vanessa P Houde

  • PubMed: 40013015
  • DOI: 10.1080/20002297.2025.2469894

  1 Insight on

  • Reduced Inflammatory Response

  • Low evidence

  the cell-free supernatants of these strains significantly reduced P. gingivalis-induced secretion of interleukins IL-6 and IL-8 by keratinocytes and TNF-α and IL-6 by U937 macrophage-like cells

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes