Effect of Probiotic Lactobacillus salivarius UBL S22 and Prebiotic Fructo-oligosaccharide on Serum Lipids, Inflammatory Markers, Insulin Sensitivity, and Gut Bacteria in Healthy Young Volunteers
- 2014-10-20
- RCT · n = 45
- Journal of Cardiovascular Pharmacology and Therapeutics 20(3)
- H. Rajkumar
- Manoj Kumar
- Nilita Das
- Subramanian Hari Subbish Kumar
- Hanumanth R. Challa
- R. Nagpal
- PubMed: 25331262
- DOI: 10.1177/1074248414555004
- High evidence
- Highly Cited
After 6 weeks, a significant reduction (P < .05) in total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides and increase in high-density lipoprotein cholesterol was observed in the probiotic as well as in the synbiotic group when compared to placebo; however, the results of total cholesterol and LDL-cholesterol were more pronounced in the synbiotic group.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes