Modulation of the immune response and metabolism in germ-free rats colonized by the probiotic Lactobacillus salivarius LI01
- 2021-01-19
- Clinical Trial · n = 2
- Applied Microbiology and Biotechnology 105(4)
- Jiafeng Xia
- Shiman Jiang
- L. Lv
- Wen-rui Wu
- Qiangqiang Wang
- Qiaomai Xu
- Jianzhong Ye
- D. Fang
- Yating Li
- Jingjing Wu
- Xiaoyuan Bian
- Liya Yang
- Huiyong Jiang
- Kaicen Wang
- Ren Yan
- Lanjuan Li
- PubMed: 33507355
- DOI: 10.1007/s00253-021-11099-z
- Low evidence
- Animal Study
The levels of serum biomarkers, such as interleukin (IL)-1α, IL-5, and IL-10, were restored by L. salivarius LI01, which indicated the activation of Th0 cell differentiation toward immune homeostasis.
- Effect
- Beneficial
- Effect size
- Moderate