Safety assessment of the human milk-isolated probiotic Lactobacillus salivarius CECT5713.
- 2007-08
- RCT · n = 50
- Journal of Dairy Science 90(8)
- F. Lara‐Villoslada
- S. Sierra
- M. Díaz-Ropero
- M. Olivares
- J. Xaus
- PubMed: 17638967
- DOI: 10.3168/JDS.2006-685
- Low evidence
- Animal Study
Intraperitoneal administration caused a significant bacterial translocation to the liver and spleen, but not to the blood. However, this translocation was not related to illness or death at either d 2 or d 5, although an increase in plasma serum alpha-amyloid protein was observed at d 2.
- Effect
- Harmful
- Effect size
- Large