Lactobacillus salivarius UALs07 and Improved Periodontal Health

• Probiotic effects of orally administered Lactobacillus salivarius WB21-containing tablets on periodontopathic bacteria: a double-blinded, placebo-controlled, randomized clinical trial.

  • 2009-05-18
  • RCT · n = 66
  • Journal of Clinical Periodontology 36(6)
  • • G. Mayanagi
    • Moto Kimura
    • S. Nakaya
    • H. Hirata
    • M. Sakamoto
    • Y. Benno
    • H. Shimauchi

  • PubMed: 19453574
  • DOI: 10.1111/j.1600-051X.2009.01392.x

  5 Insights on

  • Improved Periodontal Health

  • High evidence
  • Highly Cited
  • Clinical

  Oral administration of probiotic lactobacilli reduced the numerical sum of five selected periodontopathic bacteria and could contribute to the beneficial effects on periodontal conditions.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Improvement of periodontal condition by probiotics with Lactobacillus salivarius WB21: a randomized, double-blind, placebo-controlled study.

  • 2008-09-12
  • RCT · n = 66
  • Journal of Clinical Periodontology 35(10)
  • • H. Shimauchi
    • G. Mayanagi
    • S. Nakaya
    • Maiko Minamibuchi
    • Yasuhiro Ito
    • K. Yamaki
    • H. Hirata

  • PubMed: 18727656
  • DOI: 10.1111/j.1600-051X.2008.01306.x

  8 Insights on

  • Improved Periodontal Health

  • High evidence
  • Highly Cited
  • Adults

  Periodontal clinical parameters were improved in both groups after an 8-week intervention.

  Effect

  Beneficial

  Effect size

  Moderate