Across 3 studies, 1 showed a moderate beneficial effect of Lactobacillus salivarius UCC118 on modulating gut microbiota, and 1 showed a small beneficial effect; 1 study reported a neutral effect. The predominant effect size is moderate, but the evidence base is small and no statistically significant findings were reported. Doses, forms, durations, and populations were not consistently reported across studies.
Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Many of the included studies did not reach statistical significance — effect may be smaller than the predominant direction suggests. All studies are review articles rather than original clinical trials, limiting causal inference. Doses, forms, and study durations were not reported, preventing dose-response or timing conclusions.
bacteriocin-producing probiotic lactic acid bacteria in the modulation of gut microbiota correcting dysbiosis
live probiotic bacteria present in some food products (which transit through the GIT) have been shown to interact with the host immune system and confer several health benefits
using dietary supplements, such as probiotics, prebiotics, and synbiotics to target the gut microbiota to regulate the disordered gut microbiota would become a potential method that benefits for preventing and treating GDM