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Evidence-Based Supplement Research
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Lactobacillus salivarius UCC118 and Reduced Gastrointestinal Infections

Research synthesisVery low evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial effects of Lactobacillus salivarius UCC118 on reducing gastrointestinal infections, with effect sizes ranging from small to moderate. The evidence is based on review-level data, with no human trials or specific dose information available. The predominant effect size is moderate, but the evidence base is very small and preliminary.

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. All studies are reviews or genomic reports, not human clinical trials; no doses, forms, or sample sizes were reported. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). None of the studies reported statistical significance, and two of the three studies had very low evidence scores.

Generated Jul 12, 2026
3 of 3 papers
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