Lactobacillus salivarius UCC118 and Reduced LDL Cholesterol

• Impact of probiotics in women with gestational diabetes mellitus on metabolic health: a randomized controlled trial.

  • 2015-04
  • RCT · n = 149
  • American journal of obstetrics and gynecology 212(4)
  • • Karen L Lindsay
    • Lorraine Brennan
    • Maria A Kennelly
    • Orla C Maguire
    • Thomas Smith
    • Sinead Curran
    • Mary Coffey
    • Michael E Foley
    • Mensud Hatunic
    • Fergus Shanahan
    • Fergus Shanahan
    • Fionnuala M McAuliffe

  • PubMed: 25687568
  • DOI: 10.1016/j.ajog.2015.02.008

  14 Insights on

  • Reduced LDL Cholesterol

  • High evidence
  • Large Human Trial
  • Pregnant Women

  late gestation-related rise in total and low-density lipoprotein (LDL) cholesterol was attenuated in the probiotic vs the placebo group (+0.08 ± 0.51 vs +0.31 ± 0.45 mmol/L LDL cholesterol, P = .011)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  daily capsule (exact dose not specified)