Lactobacillus salivarius UCC118 and Reduced Risk of Sepsis

• Colonic goblet cell-associated antigen passages mediate physiologic and beneficial translocation of live gut bacteria in preweaning mice.

  • 2025-04-01
  • Nature microbiology 10(4)
  • • Sreeram Udayan
    • Alexandria N Floyd
    • Vini John
    • Bibiana E Barrios
    • Brigida A Rusconi
    • Keely G McDonald
    • Ellen Merrick Schill
    • Devesha H Kulkarni
    • Andrew L Martin
    • Rafael Gutierrez
    • Khushi B Talati
    • Dalia L Harris
    • Sushma Sundas
    • Kayla M Burgess
    • Jocelyn T Pauta
    • Elisabeth L Joyce
    • Jacqueline D Wang
    • Leslie D Wilson
    • Kathryn A Knoop
    • Phillip I Tarr
    • Chyi-Song Hsieh
    • Rodney D Newberry

  • PubMed: 40169738
  • DOI: 10.1038/s41564-025-01965-1

  2 Insights on

  • Reduced Risk of Sepsis

  • Low evidence
  • Animal Study

  its translocation was associated with protection from systemic sepsis in vivo

  Effect

  Beneficial

  Effect size

  Moderate