Lactobacillus sporogenes and Reduced Menopausal Symptoms

Doses used in studies

CFU/day: 1 billion (median 1 billion, IQR 1 billion–1 billion) — 1 study

Time to effect

Median: 12.2 months · IQR 12.2 months–12.2 months · Range 12.2 months–12.2 months — Reported in 1 of 1 study

Safety in these studies

Overall tolerabilityNo significant differenceno significant differences between groups
mammographic density, endometrial thickness and hepatic function did not show significant differences between groups
from: Endometrial, breast and liver safety of soy isoflavones plus Lactobacillus sporogenes in p

1 of 1 paper

Endometrial, breast and liver safety of soy isoflavones plus Lactobacillus sporogenes in post-menopausal women.

2012-11-30
RCT · n = 65
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 29(3)
- Nicola Colacurci
- Pasquale De Franciscis
- Marco Atlante
- Pasquale Mancino
- Marco Monti
- Giuseppe Volpini
- Claudio Benvenuti

PubMed: 23194023
DOI: 10.3109/09513590.2012.738724

4 Insights on

Reduced Menopausal Symptoms

High evidence
Clinical

menopausal symptoms were progressively and significantly reduced in severity and frequency during treatment with soy isoflavones plus Lactobacillus sporogenes versus calcium plus vitamin D₃

Effect: Beneficial
Effect size: Moderate
Significant: Yes
Dose: 1 billion spores