Lactococcus cremoris VPro 41 and Enhanced Interleukin-10 Production

• Lactococcus lactis subsp. cremoris FC triggers IFN-γ production from NK and T cells via IL-12 and IL-18.

  • 2012-12
  • Clinical Trial
  • International Immunopharmacology 14(4)
  • • A. Kosaka
    • Huimin Yan
    • S. Ohashi
    • Yayoi Gotoh
    • Ami Sato
    • H. Tsutsui
    • T. Kaisho
    • T. Toda
    • N. Tsuji

  • PubMed: 23102661
  • DOI: 10.1016/j.intimp.2012.10.007

  8 Insights on

  • Enhanced Interleukin-10 Production

  • Low evidence
  • Animal Study

  LcFC induced the production of cytokines such as IL-10, IL-12, IL-6 and TNF-α from murine bone marrow DCs (BMDCs) via MyD88-dependent pathway.

  Effect

  Beneficial

  Effect size

  Moderate