Paecilomyces hepiali and Improved Gut Microbiota Composition

• Characteristics of exopolysaccharides from Paecilomyces hepiali and their simulated digestion and fermentation in vitro by human intestinal microbiota.

  • 2024-05
  • International journal of biological macromolecules 266
  • • Zhongwei Wu
    • Rongxian Zhang
    • Jie Wang
    • Tenglong Li
    • Guang Zhang
    • Chaohui Zhang
    • Hong Ye
    • Xiaoxiong Zeng

  • PubMed: 38552700
  • DOI: 10.1016/j.ijbiomac.2024.131198

  3 Insights on

  • Improved Gut Microbiota Composition

  • Low evidence

  The proliferation effects of PHEPSs on Bifidobacterium and Lactobacillus were weaker significantly than those of fructooligosaccharides before 12 h of fecal fermentation, but stronger after 24 h of fecal fermentation.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Positive effects of extracellular polysaccharides from Paecilomyces hepiali on immune-enhancing properties by regulating gut microbiota in cyclophosphamide-induced mice.

  • 2024-08
  • International journal of biological macromolecules 274
  • • Baoming Tian
    • Yuezhi Jiang
    • Renjian Liu
    • Yahya S Hamed
    • Ahmed M Rayan
    • Shenlu Xu
    • Peilong Sun
    • Kai Yang

  • PubMed: 38917915
  • DOI: 10.1016/j.ijbiomac.2024.133390

  2 Insights on

  • Improved Gut Microbiota Composition

  • Low evidence
  • Animal Study

  PHP increased the proliferation of beneficial bacteria... and reduced the abundance of Proteobacteria, Deferribacterota, Mucispirillum and Escherichia_Shigella, promoted the production of short-chain fatty acids

  Effect

  Beneficial

  Effect size

  Moderate