Saccharomyces boulardii and Immune Response to Rotavirus Vaccine Antigen

• Design and immunogenicity of a recombinant Saccharomyces boulardii secreting the P2-VP8 subunit rotavirus vaccine.

  • 2026-02-02
  • Clinical Trial
  • Scientific reports 16(1)
  • • Ibrahim Farhani
    • Ahad Yamchi
    • Hadi Razavi Nikoo
    • Fatemeh T Shamsabadi
    • Shahriyar Abdoli
    • R Holland Cheng
    • Majid Shahbazi

  • PubMed: 41629582
  • DOI: 10.1038/s41598-026-37374-5

  2 Insights on

  • Immune Response to Rotavirus Vaccine Antigen

  • High evidence
  • Rigorous Journal

  In vivo results denoted that recombinant Saccharomyces boulardii elicited significant differences in levels of IFN-γ and IL-4 responses compared to control groups. Furthermore, cell proliferation differences were not statistically significant.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes