Saccharomyces boulardii and Reduced Anti-Listeria Effect

• Evaluation of the delivery of an anti-Listeria endolysin via CRISPR-Cas9 engineered probiotic Saccharomyces boulardii.

  • 2026-02-26
  • Applied microbiology and biotechnology 110(1)
  • • David Sáez Moreno
    • João Paulo Carvalho
    • Ellen Murray
    • Natalia Soledad Ríos Colombo
    • Alexandre Lamas
    • Alejandra Cardelle Cobas
    • Colin Hill
    • Joana Azeredo
    • Lucília Domingues

  • PubMed: 41748831
  • DOI: 10.1007/s00253-026-13749-6

  3 Insights on

  • Reduced Anti-Listeria Effect

  • Low evidence

  the anti-Listeria effect was reduced potentially due to the lower metabolic activity of S. boulardii and the higher competition with the intestinal microbiome

  Effect

  Harmful

  Effect size

  Small