Saccharomyces cerevisiae and Improved Constipation

• Laxative effects of triple fermented barley extracts (FBe) on loperamide (LP)-induced constipation in rats.

  • 2019-06-21
  • n = 48
  • BMC complementary and alternative medicine 19(1)
  • • Jong-Min Lim
    • Young Dae Kim
    • Chang-Hyun Song
    • Su-Jin Park
    • Dong-Chan Park
    • Hyung-Rae Cho
    • Go-Woon Jung
    • Khawaja Muhammad Imran Bashir
    • Sae Kwang Ku
    • Jae-Suk Choi

  • PubMed: 31226979
  • DOI: 10.1186/s12906-019-2557-x

  1 Insight on

  • Improved Constipation

  • Low evidence

  oral administration of 100-300 mg/kg of FBe exhibited promising laxative properties including intestinal charcoal transit ratio, thicknesses and mucous producing goblet cells of colonic mucosa with decreases of fecal pellet numbers and mean diameters remained in the lumen of colon, mediated by increases in gastrointestinal motility.

  Effect

  Beneficial

  Effect size

  Moderate

• Laxative effects of fermented rice extract in rats with loperamide-induced constipation.

  • 2014-10-17
  • Experimental and therapeutic medicine 8(6)
  • • Jae-Suk Choi
    • Joo Wan Kim
    • Hyung-Rae Cho
    • Ki-Young Kim
    • Jong-Kwang Lee
    • Jae Hak Sohn
    • Sae-Kwang Ku

  • PubMed: 25371743
  • DOI: 10.3892/etm.2014.2030

  3 Insights on

  • Improved Constipation

  • Low evidence

  These conditions were significantly alleviated following the administration of the three doses of FRe when compared with the loperamide control group.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes