Saccharomyces cerevisiae and Reduced Clostridium Difficile Growth

• Potent Antimicrobial Activity of Aspergillus oryzae Fermentate Against Toxigenic Strains of Clostridioides difficile.

  • 2025-03-22
  • Antibiotics (Basel, Switzerland) 14(4)
  • • Ahmad Alshannaq
    • Morgan Henning
    • Jonah Dixon
    • Colleen Riley
    • Dasol Choi
    • Jae-Hyuk Yu
    • Nasia Safdar

  • PubMed: 40298462
  • DOI: 10.3390/antibiotics14040333

  2 Insights on

  • Reduced Clostridium Difficile Growth

  • Low evidence

  The ethyl acetate extract of A. oryzae fermentate (fungal extract) exhibited potent bactericidal activity, producing a significant zone of inhibition across all tested C. difficile strains... Time kill assays further confirmed the rapid bactericidal effect of the fungal extract, achieving complete C. difficile eradication within six hours.

  Effect

  Beneficial

  Effect size

  Large