Saccharomyces cerevisiae and Reduced Cold/Flu Severity

• Efficacy of a yeast postbiotic on cold/flu symptoms in healthy children: A randomized-controlled trial.

  • 2024-06-28
  • RCT
  • Pediatric research 96(7)
  • • Ruma G Singh
    • Vicenta Garcia-Campayo
    • Justin B Green
    • Neil Paton
    • Julissa D Saunders
    • Huda Al-Wahsh
    • David C Crowley
    • Erin D Lewis
    • Malkanthi Evans
    • Marc Moulin

  • PubMed: 38942887
  • DOI: 10.1038/s41390-024-03331-z

  2 Insights on

  • Reduced Cold/Flu Severity

  • High evidence

  Total CARIFS severity scores, 'sore throat' and 'muscle aches or pains' symptom scores in the EpiCor group were significantly lower compared to Placebo during incidences of cold/flu (P ≤ 0.05).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics.

  • 2021-05-04
  • Review
  • Nature reviews. Gastroenterology & hepatology 18(9)
  • • Seppo Salminen
    • Maria Carmen Collado
    • Akihito Endo
    • Colin Hill
    • Sarah Lebeer
    • Eamonn M M Quigley
    • Mary Ellen Sanders
    • Raanan Shamir
    • Jonathan R Swann
    • Hania Szajewska
    • Gabriel Vinderola

  • PubMed: 33948025
  • DOI: 10.1038/s41575-021-00440-6

  6 Insights on

  • Reduced Cold/Flu Severity

  • Moderate evidence
  • Highly Cited

  Compared with placebo, participants consuming Saccharomyces cerevisiae fermentate had fewer self-reported upper respiratory tract infections, less severe cold/flu symptoms, and fewer missed work or school days.

  Effect

  Beneficial

  Effect size

  Moderate