In vitro digestion and fermentation of ginseng pectic polysaccharide GPS-1 and attenuation of its product on oleic acid-induced oxidative stress in HepG2 cells.
- 2026-02-18
- Frontiers in pharmacology 17
- Xiwen Sun
- Li Liu
- Wenbo Jiao
- Ting Ren
- Ran Zhao
- Zirui Tan
- Ziye Jiang
- Jing Wang
- Bo Li
- Xiaoyu Zhang
- Lili Jiao
- PubMed: 41788794
- DOI: 10.3389/fphar.2026.1758770
- Low evidence
the fermented product GPS-1-I48 exhibited significantly enhanced hepatoprotective activity, increasing SOD, CAT, and GSH-Px activities while reducing MDA and TG levels in HepG2 cells
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes