Streptococcus salivarius M18 and Reduced Gingival Bleeding

• A Three-Month Probiotic (the Streptococcus salivarius M18 Strain) Supplementation Decreases Gingival Bleeding and Plaque Accumulation: A Randomized Clinical Trial.

  • 2024-07-18
  • RCT · n = 60
  • Dentistry journal 12(7)
  • • Ksenia Babina
    • Dilara Salikhova
    • Irina Makeeva
    • Alexandr Zaytsev
    • Inna Sokhova
    • Sevil Musaeva
    • Maria Polyakova
    • Nina Novozhilova

  • PubMed: 39057009
  • DOI: 10.3390/dj12070222

  3 Insights on

  • Reduced Gingival Bleeding

  • High evidence

  Probiotic supplementation resulted in a significant decrease in gingival bleeding at 1 month (effect size 1.09 [CI95%: 0.55-1.63]), 2 months (effect size 0.78 [CI95%: 0.26-1.30]), and 3 months (effect size 0.67 [CI95%: 0.15-1.18])

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Antigingivitis and Antiplaque Effects of Oral Probiotic Containing the Streptococcus salivarius M18 Strain: A Randomized Clinical Trial

  • 2023-09-06
  • RCT · n = 61
  • Nutrients 15(18)
  • • K. Babina
    • Dilara Salikhova
    • V. Doroshina
    • Irina Makeeva
    • A. Zaytsev
    • Matvey Uvarichev
    • M. Polyakova
    • N. Novozhilova

  • PubMed: 37764667
  • DOI: 10.3390/nu15183882

  5 Insights on

  • Reduced Gingival Bleeding

  • High evidence

  The Gingival Bleeding Index also decreased significantly in the probiotic group after the intervention period; after the follow-up, this parameter did not differ significantly in both groups from the baseline values.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes