Efficacy and acceptability of different probiotic products plus laxatives for pediatric functional constipation: a network meta-analysis of randomized controlled trials.
- 2024-05-29
- Meta-Analysis · n = 710
- European journal of pediatrics 183(8)
- Wei-Chieh Yang
- Bing-Syuan Zeng
- Chih-Sung Liang
- Chih-Wei Hsu
- Kuan-Pin Su
- Yi-Cheng Wu
- Yu-Kang Tu
- Pao-Yen Lin
- Brendon Stubbs
- Tien-Yu Chen
- Yen-Wen Chen
- Yow-Ling Shiue
- Bing-Yan Zeng
- Mein-Woei Suen
- Chao-Ming Hung
- Ming-Kung Wu
- Ping-Tao Tseng
- PubMed: 38806862
- DOI: 10.1007/s00431-024-05568-6
- High evidence
Protexin plus laxatives (standardized mean difference (SMD) = 1.87, 95% confidence interval (95% CI) = 0.85 to 2.90) were associated with the greatest improvement in bowel movement or stool frequency among all the investigated probiotic products.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes