Atopic dermatitis, also known as eczema, is a chronic inflammatory skin condition characterized by symptoms such as intense itching, dryness, and redness. Various oral vitamins and nutritional supplements have been explored for their potential to alleviate atopic dermatitis symptoms. Here are some supplements that have shown some level of efficacy based on current research:

1. Probiotics: Multiple studies have shown that certain strains of probiotics, such as Lactiplantibacillus plantarum, Ligilactobacillus salivarius, and Lactobacillus acidophilus, may help improve symptoms of atopic dermatitis¹. Probiotics help maintain a healthy balance of gut bacteria, which can influence the immune system and inflammation.

2. Vitamin D: Vitamin D supplementation has been found to improve the severity of atopic dermatitis in several studies. Low levels of serum vitamin D are commonly found in individuals with atopic dermatitis, and supplementation could help reduce symptoms²³⁴.

3. Vitamin E: Some studies have reported that Vitamin E, especially when combined with Vitamin D, can significantly improve atopic dermatitis symptoms⁵. The antioxidant properties of Vitamin E might help reduce inflammation.

4. Fish Oil/Omega-3 Fatty Acids: Although the data is limited, fish oil supplements which are rich in omega-3 fatty acids have anti-inflammatory properties that might benefit those with atopic dermatitis⁶.

5. Herbal Supplements: Specific compounds like Zemaphyte, kefir, and freeze-dried whey with Cuscuta campestris Yuncker extract have shown potential in clinical trials¹. However, more extensive research is needed to confirm their effectiveness.

Despite these promising results, the evidence is not yet strong enough to support routine use of any one supplement for treating atopic dermatitis. More extensive, randomized controlled trials are required to establish definitive guidelines.

Would you like to see a list of specific supplement products that contain any of these ingredients?

Footnotes

1. Isaac Weber, "Clinical Efficacy of Nutritional Supplements in Atopic Dermatitis," PubMed, 2023. ↩ ↩²

2. Min Jung Kim, "Vitamin D Status and Efficacy of Vitamin D Supplementation in Atopic Dermatitis," NCBI, 2016. ↩

3. Kleyton de Carvalho Mesquita, "Atopic dermatitis and vitamin D: facts and controversies," NCBI, 2013. ↩

4. Afif Nurul Hidayati, "Efficacy of vitamin D supplementation on the severity of atopic dermatitis in children," NCBI, 2025. ↩

5. Allison L. Goddard, "Alternative, Complementary, and Forgotten Remedies for Atopic Dermatitis," NCBI, 2015. ↩

6. Megan J. Schlichte, "Diet and eczema: a review of dietary supplements for the treatment of atopic dermatitis," NCBI, 2016. ↩