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Guidelines for Safeguarding Your Gut Microbiome While Taking Amoxicillin

Learn how to protect and restore your gut microbiome with probiotics and dietary fiber during and after antibiotic treatment. Discover key probiotic strains like Lactobacillus and Saccharomyces boulardii, and how a fiber-rich diet can help maintain a healthy gut.

  • Prescribed Amoxicillin - recommendations?
    Hey all,

    I’m having a persistent throat infection and was prescribed amoxicillin: I’d love some guides on what can I do prior to taking, during and post taking to help protect my microbiomes and renew it post antibiotics.

    Thanks! 🙏

  • When taking antibiotics like Amoxicillin, it's essential to consider measures to protect and restore your gut microbiome. Here's a guide on what you can do before, during, and after antibiotic treatment:

    Before and During Antibiotic Treatment

    1. Probiotics:

      • Lactobacillus and Bifidobacterium: These are common probiotic strains that can help maintain a healthy balance of gut bacteria and reduce antibiotic-associated diarrhea (AAD).
      • Saccharomyces boulardii: A yeast probiotic shown to be effective in preventing and reducing the occurrence of diarrhea associated with antibiotic treatment. It also enhances the recovery of bacterial populations post-antibiotics1.

    2. Dietary Fiber:

      • Prebiotic Fiber: Consuming dietary fibers such as inulin, fructooligosaccharides (FOS), and galactooligosaccharides (GOS) can modulate the gut environment favorably. Fiber supplementation during antibiotics can help reduce gut dysbiosis by maintaining a lower redox potential and promoting a balanced microbiome2.

    After Antibiotic Treatment

    1. Continued Probiotic Use:

      • Continuing the use of probiotics like Saccharomyces boulardii for a week or more after completing the antibiotic course can help restore the gut's bacterial equilibrium3.

    2. Prebiotic and Fiber-Rich Diet:

      • Including a variety of fiber-rich foods such as fruits, vegetables, beans, and whole grains in your diet can further support the growth of beneficial gut bacteria.

    Summary of Recommendations

    • Probiotics to Take:

      • Lactobacillus and Bifidobacterium strains
      • Saccharomyces boulardii

    • Dietary Additions:

      • Prebiotic Fiber (inulin, FOS, GOS)

    Would you like me to search for specific products that contain these ingredients?

    Footnotes

    1. Madeleine Spatz, "Saccharomyces boulardii CNCM I-745 supplementation during and after antibiotic treatment positively influences the bacterial gut microbiota," Front Med (Lausanne), 2023. ↩

    2. Swathi Penumutchu, "Fiber supplementation protects from antibiotic-induced gut microbiome dysbiosis by modulating gut redox potential," Nat Commun, 2024. ↩

    3. Blake Rodgers, "Prescribing an antibiotic? Pair it with probiotics," J Fam Pract, 2013. ↩

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