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Navigating Probiotic Intolerance: Exploring Alternatives for Gut Health

Struggling with probiotic intolerance and histamine issues, the user seeks advice on prebiotics and alternative strategies to support gut health. Potential solutions discussed include specific prebiotic foods, cautious use of fermented foods, and consulting health professionals.


  • Unable to tolerate any probiotics supplements
    Seemingly unable to tolerate any probiotics, no matter how safe or high quality they are.

    Have tried optibac every day, optibac every day extra, custom probiotics d lactate free, l rhamnosus gg single strain, florastor s boulardi. Negative reactions from all of them despite giving them all a while to help and also starting at the lowest conceivable dose.

    Anyone else had this issue and what alternatives have you managed to find success from? I’m thinking perhaps a purely prebiotic focus might be best, and retrying probiotic foods (although I do have severe histamine intolerance so not sure this is viable)

  • It sounds like you're experiencing significant challenges with probiotic supplements, which can be particularly frustrating if you're looking to improve your gut health. Here are some considerations and alternatives you might explore:

    1. Prebiotics: Since you mentioned a potential focus on prebiotics, these could be a viable alternative. Prebiotics are non-digestible fibers that feed beneficial bacteria in the gut[^1]. They can help support a healthy gut environment without directly adding new bacteria like probiotics. Common prebiotics include inulin, fructooligosaccharides (FOS), and galactooligosaccharides (GOS).

    2. Specific Prebiotic Foods: Foods rich in prebiotics include garlic, onions, leeks, asparagus, bananas, and oats[^1]. These can support your gut health naturally without using supplements.

    3. Hydrolyzed or Fermented Foods: If you can tolerate them, incorporating small amounts of fermented foods gradually might help. However, these can sometimes trigger histamine intolerance symptoms so proceeding with caution is key[^2]. If histamine is a concern, you might also consider working with a healthcare provider to identify which fermented foods might be less problematic for you.

    4. Histamine Degrading Probiotics: While you're seemingly intolerant to many strains, some research suggests that specific bacterial strains, such as Bifidobacterium infantis, might help reduce histamine production in the gut[^3].

    5. Consult a Specialist: Because of the complexity with histamine intolerance and probiotics, consulting a healthcare professional, particularly a gastroenterologist or a dietitian with experience in gut health, may provide personalized insights.

    While pursuing these alternatives, it's essential to ensure any new addition or change is done gradually and in consultation with healthcare providers, especially considering your histamine intolerance.

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