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Exploring Probiotic Efficacy: Live Bacteria vs. Natural Sources

Discussing the effectiveness and viability of probiotic capsules, including CFU counts and natural alternatives like fermented foods. Examines research on bacterial survival and the benefits of non-capsule probiotic forms for a more natural approach.


  • Probiotic capsules efficacy? dead bacteria?

    I have been researching the market for market for a probiotic supplement that fits my needs, but after thorough research, I found that capsules and pills are freeze-dried bacteria. Most people like to rate their choice by CFU count (number of bacteria), but this seems very misleading as the bacteria are not live and in an alkaline state. I mean, how many bacteria actually survive and are viable?

    I don’t think an artificially processed supplement is the way to go for my needs, which leads me to my question: Have anyone done any research on a more natural probiotic supplement? I know that the best is to get my sources from foods, but in case I’m looking for the best possible supplement.

  • The efficacy and viability of probiotic capsules are subjects of significant interest. The survival and effectiveness of probiotics are influenced by various factors, including their delivery form, storage conditions, and the viability of bacteria upon consumption.

    1. Viability of Bacteria in Probiotic Capsules: A study examined the viability of three commercial probiotic strains (Bifidobacterium longum, Lactobacillus acidophilus, and Bacillus subtilis) in harsh conditions simulating a journey to Mars. It was found that while exposure to cosmic radiation had minimal effects on these strains, their survival varied during passage through simulations of the upper gastrointestinal (GI) tract1.

    2. Natural vs. Synthetic Probiotic Supplements: There is growing interest in developing non-capsule forms of probiotics, often derived from naturally fermented foods. Some research suggests that natural food sources of probiotics may offer a holistic benefit due to the combination of living bacteria and the presence of other beneficial compounds2.

    3. Efficacy of Non-Capsule Probiotic Forms: The efficacy of probiotics also extends to natural sources like fermented dairy and non-dairy products, such as yogurt and kefir. These forms may harbor more viable and active bacteria compared to some commercially produced capsules, especially if manufacturing and storage lead to loss of bacterial viability3.

    Given the diverse factors impacting probiotic efficacy, choosing a product from a reliable manufacturer that ensures appropriate storage and bioavailability could be crucial. If you're interested in natural sources, consuming fermented foods is often recommended.

    If you are considering a shift to more natural options or are looking for recommendations on specific products, please let me know if you are interested in searching for some product options available on Pillser.

    Footnotes

    1. Patricia Fajardo-Cavazos, "Shelf Life and Simulated Gastrointestinal Tract Survival of Selected Commercial Probiotics During a Simulated Round-Trip Journey to Mars," PMC, 2021.

    2. Guangqiang Wang, "Characteristics of Probiotic Preparations and Their Applications," PMC, 2022.

    3. Ibid.

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