Small Intestinal Bacterial Overgrowth (SIBO) is a condition characterized by an abnormal increase in the overall bacterial population in the small intestine. Treatments often focus on reducing bacterial overgrowth and addressing nutritional deficiencies.

Supplement Recommendations for SIBO

1. Vitamin B-12: People with SIBO may need intramuscular injections of vitamin B-12, especially if there's a significant deficiency¹.
2. Oral Vitamins: Supplementation may include other vitamins such as vitamin D, vitamin K, and other B vitamins to combat deficiencies¹.
3. Calcium and Iron Supplements: These are important if there are deficiencies in minerals, which can commonly occur with SIBO¹.
4. Probiotics: Although not mentioned directly in the sources, probiotics are often considered to help balance gut bacteria. However, their efficacy can vary, and they should be used under the guidance of a healthcare professional¹.
5. Digestive Enzymes: To improve nutrient absorption, digestive enzymes can sometimes be recommended¹.

Dietary Considerations

• Lactose-Free Diet: A lactose-free diet may be necessary, as SIBO can cause lactose intolerance¹.
• Low FODMAP Diet: Often recommended, this diet limits fermentable carbohydrates that feed the bacteria in the small intestine¹.
• Yogurt: Some individuals may tolerate lactose-free or low-lactose yogurt due to the natural breakdown of lactose by the bacteria used in yogurt cultures¹.

Antibiotic Treatment

Antibiotic therapy is a common treatment to reduce bacterial overgrowth. However, the bacteria can return after discontinuation of antibiotics, so long-term management may be necessary².

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Footnotes

1. Small Intestinal Bacterial Overgrowth (SIBO) - Mayo Clinic ↩ ↩² ↩³ ↩⁴ ↩⁵ ↩⁶ ↩⁷ ↩⁸

2. Small Intestinal Bacterial Overgrowth (SIBO) - Mayo Clinic ↩