Considering SAMe and Levothyroxine: Timing for Effective Use
Explore potential interactions and optimal timing when taking SAMe alongside levothyroxine. Discusses the importance of separating these supplements to ensure proper absorption, with advice to consult your healthcare provider for personalized guidance.
Real quick: taking SAMe at the same time as levothyroxine. Thoughts?
Title. I take levothyroxine first thing when I get up. Can I take SAMe with it?
There is limited specific information regarding the interaction between SAMe (S-adenosylmethionine) and levothyroxine. However, levothyroxine is known to interact with several other substances, such as iron, calcium, and certain medications, potentially affecting its absorption and effectiveness1. As a general rule, it's advisable to take levothyroxine on an empty stomach and separate from other medications or supplements by at least 30 to 60 minutes to ensure optimal absorption.
Given this information, it might be prudent to separate the intake of SAMe and levothyroxine to avoid any potential absorption issues. It's always best to consult with your healthcare provider for personalized advice based on your specific health needs and medication regimen.
Footnotes
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Savannah A Irving, "Drugs that interact with levothyroxine: an observational study from the Thyroid Epidemiology, Audit and Research Study (TEARS) - PubMed," PubMed, 2014. ↩
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