Skip to main content
Supplement Research and Comparison Website•Best Price Guarantee
Supplement Research and Comparison Website
Pillser
Search
Sign UpLog In

Effective Supplements for Chronic Fatigue Syndrome (CFS): CoQ10, Melatonin, Zinc, and More

Explore how supplements like CoQ10, NADH, melatonin, zinc, selenium, and yeast beta-glucan with multivitamins can help manage Chronic Fatigue Syndrome (CFS) by reducing fatigue and improving quality of life. Backed by clinical studies, these supplements offer promising benefits.

  • Clinically proven effective supplements for CFS

  • Several supplements have been explored for their potential effectiveness in managing Chronic Fatigue Syndrome (CFS). Studies suggest the following supplements might offer some benefits:

    1. Coenzyme Q10 (CoQ10) and NADH:

      • CoQ10 and NADH are antioxidants that may help improve cellular energy production by facilitating ATP synthesis. Clinical trials have shown improvements in fatigue and health-related quality of life with CoQ10 (200 mg) plus NADH (20 mg) co-supplementation12.

    2. Melatonin and Zinc:

      • Supplementation with melatonin and zinc has been found to reduce physical fatigue and improve sleep quality. Melatonin (1 mg) and zinc (10 mg) taken daily for 16 weeks showed significant improvements compared to placebo3.

    3. Coenzyme Q10 plus Selenium:

      • Another combination showing promise includes CoQ10 (400 mg) and selenium (200 µg) daily. This combination has been associated with reduced overall fatigue and improved quality of life, likely due to their antioxidant and anti-inflammatory properties4.

    4. Yeast Beta-Glucan with Multivitamins:

      • Beta-glucan, along with vitamins D3, B6, and zinc, has shown potential in alleviating cognitive fatigue and improving overall quality of life in CFS patients5.

    5. Ubiquinol (Reduced form of CoQ10):

      • Ubiquinol has demonstrated significant anti-fatigue effects in both CFS patients and healthy individuals when taken daily. It appears to improve cognitive performance and reduce subjective fatigue6.

    It's important to note that while some studies have shown positive effects, others have had mixed or inconclusive results, highlighting the need for further research in this area. If you are considering supplementing for CFS, it is advisable to consult with a healthcare professional.

    Footnotes

    1. Clinical Nutrition, "Effect of dietary Coenzyme Q10 plus NADH supplementation on fatigue perception and health-related quality of life in individuals with chronic fatigue syndrome." ↩

    2. PubMed, "Effect of dietary CoQ10 plus NADH co-supplementation on cognitive fatigue and overall fatigue impact in ME/CFS patients." ↩

    3. PubMed, "Effect of melatonin plus zinc supplementation on fatigue perception in chronic fatigue syndrome." ↩

    4. Antioxidants & Redox Signaling, "Coenzyme Q10 plus selenium supplementation for ME/CFS." ↩

    5. Nutrients, "Yeast beta-glucan supplementation with multivitamins for cognitive impairment in chronic fatigue syndrome." ↩

    6. Journal of Nutritional Biochemistry, "Ubiquinol-10 intake in chronic fatigue syndrome and its effects on fatigue and sleep." ↩

New Topic

Browse Related Questions

Back to top