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Exploring Alternatives for Intrinsic Factor Supplements to Combat Chronic Fatigue

A user shares their struggle with chronic fatigue and past success using a B-complex with intrinsic factor from Douglas Laboratories. Seeking advice due to discontinuation of the product, the user queries about effective alternatives and supplementation strategies.


  • So, years ago (2017ish) I had another round of chronic fatigue and after digging I did find out about Intrinsic factor and starting using DOUGLAS LABORATORIES B Complex WITH Intrinsic Factor.. That, along with D3 supplementation and a KETO diet.

    There was a nice window where I felt great. My mood, energy, all improved. all inflammation in my joints went away. I had no anxiety.. I just felt NORMAL.. that lasted for a few months and then went down .. and then the pandemic hit and everything went wompus.

    around 2020 I was trying to get my supplement on Amazon and elsewhere and they no longer carried it. I even called Douglas Labs to ask if they would be producing more and they said no.. :(.

    I see a couple of other supplements with Intrinsic factor, one that i seem to ahve tried but don't know why I didn't continue.. (was it not working as well? I o don't know)l.

    So here I am AGAIN with another round of fatigue and issues. I am on Adderal as well as Carbanazapene and I take Estradiol and Progsterone. I have ADHD and finances are tight so trying to remain consistant with a good solid protocol has been hard.

    SO has anyone had luck with an intrinsifc factor supplement?

  • Intrinsic factor is necessary for the absorption of vitamin B12, which is essential for red blood cell formation and the functioning of the brain and nerves1. Deficiencies in vitamin B12, which can occur due to a lack of intrinsic factor (often seen in conditions like pernicious anemia), can result in fatigue, lethargy, anemia, and neurological issues2.

    Patients with chronic fatigue syndrome or myalgic encephalomyelitis may respond favorably to vitamin B12 injections combined with oral folic acid3. However, individual responses can vary significantly. There have been case reports showing improvement in symptoms like lethargy and fatigue upon administration of vitamin B124.

    Given your history and the described effectiveness of intrinsic factor supplements for your condition, there could be benefit in continuing with a similar supplementation approach. Since the cessation of the Douglas Laboratories product, consider exploring other supplements containing intrinsic factor.

    Would you like me to look for product recommendations containing intrinsic factor available on Pillser?

    Footnotes

    1. Harvard T.H. Chan School of Public Health, "Vitamin B12"

    2. Elena Azzini, "A Brief Review on Vitamin B12 Deficiency Looking at Some Case Study Reports in Adults"

    3. Björn Regland, "Response to Vitamin B12 and Folic Acid in Myalgic Encephalomyelitis and Fibromyalgia"

    4. Elena Azzini, "A Brief Review on Vitamin B12 Deficiency Looking at Some Case Study Reports in Adults"

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