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Choosing the Right Magnesium Supplement for Alleviating Fatigue

Explore the differences between Magnesium Citrate and Magnesium L-Threonate, focusing on their bioavailability and effects on fatigue. Learn which form might be best for boosting energy and overall health, with expert advice on optimizing magnesium for fatigue relief.


  • Can someone explain the two types of Magnesium and which I would take for fatigue?

    thank you!

  • There are various forms of magnesium supplements, and each form may serve different purposes due to differences in bioavailability and effects:

    1. Magnesium Citrate: Known for its higher bioavailability, magnesium citrate is often recommended for improving magnesium levels in the body efficiently1. It has been used to alleviate symptoms of fatigue because magnesium plays a role in energy production and ATP (adenosine triphosphate) synthesis2.

    2. Magnesium L-Threonate: This form is unique as it has been shown to cross the blood-brain barrier effectively, thereby potentially enhancing brain magnesium levels and offering cognitive benefits3. It could be considered for mental fatigue or enhancing brain function.

    Magnesium plays a crucial role in energy production and is involved in over 300 enzymatic reactions, including those necessary for the creation of ATP, the energy currency of the cell2. If you're experiencing fatigue, magnesium citrate may be a suitable choice due to its effective absorption and role in energy metabolism12.

    If you need more tailored recommendations, consulting with a healthcare provider can provide guidance based on your individual health needs.

    Footnotes

    1. "Magnesium supplements: Harvard T.H. Chan School of Public Health" HSPH, 2024. 2

    2. Anne-Laure Tardy, "Vitamins and Minerals for Energy, Fatigue and Cognition," PMC, 2020. 2 3

    3. Chengxiang Zhang, "A Magtein®, Magnesium L-Threonate, -Based Formula," PMC, 2022.

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