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Understanding Vitamin B12 Deficiency: Causes, Symptoms, and Treatment Options

A user concerned about their low vitamin B12 levels discusses with an assistant the implications of a 105 pg/mL result. The conversation covers symptoms, potential treatments like injections and supplements, and the importance of consulting a healthcare provider for personalized advice.


  • 105

    Hey! I just had some blood work done and my B12 came back as 105pg/mL. After a bit of research it looks like under 300 is out of normal range but I was wondering just how bad my result is? With that I was wondering what the treatment looks like? Will I need injections or are there other options like a standard supplement?

    Thank you for your help!!

  • A vitamin B12 level of 105 pg/mL is considered below the normal range. Typically, levels below 200 to 250 pg/mL are seen as suboptimal, with symptoms potentially manifesting when the level drops further1. Vitamin B12 deficiency can lead to a variety of symptoms, including fatigue, pale skin, neurological changes such as numbness and tingling, and potentially more severe conditions like megaloblastic anemia2.

    For treating vitamin B12 deficiency, especially at levels as low as yours, the initial approach usually involves vitamin B12 injections, known as hydroxocobalamin, which might be administered every other day for two weeks3. This is often necessary to quickly restore the vitamin levels and address any symptoms you're experiencing.

    After the initial treatment with injections, if dietary deficiencies are the cause, you may continue with oral B12 supplements or periodic injections depending on the underlying reason for the deficiency4. If the B12 deficiency is related to dietary insufficiency, it might involve ensuring adequate intake of B12-rich foods, such as meat, fish, dairy, and fortified cereals5.

    Given your result, it's essential to discuss with a healthcare provider to determine the best course of action tailored to your specific needs, considering factors like the root cause of your deficiency and any symptoms you may have.

    Footnotes

    1. Office of Dietary Supplements - Vitamin B12

    2. Office of Dietary Supplements - Vitamin B12

    3. NHS - Treatment of Vitamin B12 or Folate Deficiency Anemia

    4. NHS - Vitamin B12 or folate deficiency anaemia

    5. NHS - Vitamin B12 or folate deficiency anaemia

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