There is limited specific information available on the direct effects of collagen hydrolysate on bilirubin levels. Collagen hydrolysate is a protein supplement derived from collagen that is typically used to improve skin health, joint function, and overall connective tissue support. Its impact on liver function or bilirubin levels is not well-documented in scientific literature.

Bilirubin is a substance produced by the normal breakdown of red blood cells and is processed by the liver. If you are concerned about bilirubin levels or liver health, it is best to consult a healthcare professional for advice tailored to your specific health needs. They might be able to provide guidance on how different supplements, including collagen, may interact with liver function.

L-glutamine is generally considered safe and does not commonly affect bilirubin levels or liver function in individuals with normal hepatic function. Clinical trials have not reported serious liver-related adverse events associated with L-glutamine¹. However, in patients with advanced liver diseases such as cirrhosis, glutamine supplementation could potentially worsen hepatic encephalopathy. This is due to its metabolism into glutamate and ammonia, which can increase ammonia levels in the blood, but it doesn't directly affect bilirubin¹. Therefore, while glutamine itself is unlikely to significantly impact bilirubin, care should be taken in individuals with existing severe liver conditions.

Footnotes

1. Weaver SB, Rungkitwattanakul D, Singh D. "L-Glutamine - LiverTox - NCBI Bookshelf." NCBI, LiverTox. ↩ ↩²