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Supplement Recommendations for Longevity and Cognitive Health Enhancement

Explore a comprehensive supplement protocol to support longevity and prevent cognitive decline for older adults. Discussion includes B Vitamins, Vitamin D, Omega-3s, antioxidants, and curcumin, alongside existing supplementation of taurine, creatine, magnesium glycinate, and a multivitamin.

  • Looking for a supplement protocol for my father to increase longevity and prevent cognitive decline. He is currently taking taurine, creatine, magnesium glycinate and a multivitamin. Any other obvious suggestions?

  • For a supplement protocol to increase longevity and prevent cognitive decline, the following additional supplements are suggested based on current research:

    1. B Vitamins: Supplementing with B vitamins, particularly B6, B9 (folate), and B12, could help reduce homocysteine levels, which is associated with a lower risk of cognitive decline and dementia1.

    2. Vitamin D: Adequate vitamin D levels are important for overall health and can play a significant role in longevity and cognitive function. Many individuals have suboptimal vitamin D levels, and supplementation can help mitigate this2.

    3. Omega-3 Fatty Acids: Omega-3s, particularly DHA and EPA, are vital for brain health and can help prevent cognitive decline. They are found in fish oil and algal oil supplements3.

    4. Antioxidants: Supplements like vitamin E and selenium provide antioxidative benefits, which can help protect against cognitive decline by reducing oxidative stress4.

    5. Curcumin: Found in turmeric, curcumin has anti-inflammatory and antioxidant properties which may contribute to longevity and improved cognitive function5.

    Each of these supplements addresses important aspects of aging and cognitive health. However, it's crucial to consult with a healthcare professional before starting any new supplement regimen to ensure safety and efficacy, especially if there are any pre-existing health conditions or medications involved.

    Footnotes

    1. Zhibin Wang, "B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis," PubMed, 2022. ↩

    2. Bruce N. Ames, "Prolonging healthy aging: Longevity vitamins and proteins," NCBI, 2018. ↩

    3. Michael Fenech, "Vitamins Associated with Brain Aging, Mild Cognitive Impairment, and Alzheimer Disease," NCBI, 2017. ↩

    4. David R Thomas, "Vitamins in Aging, Health, and Longevity," NIH, 2024. ↩

    5. Mehran Izadi, "Longevity and anti-aging effects of curcumin supplementation," NCBI, 2024. ↩

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