Creating a Comprehensive Supplement Formula for Health and Longevity
In this chat, an exhaustive supplement formula with 15 essential ingredients is designed, focusing on clinically proven doses to enhance human health and longevity. The discussion also explores potential additional compounds for further boosting longevity benefits.
using published human studies , make a supplement formula using 15 ingredients with the correct clinically proven doses focused on human health and longevity
Based on the research data available on supplements that promote human health and longevity, here is a comprehensive supplement formula with 15 ingredients along with their clinically proven doses:
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Nicotinamide Mononucleotide (NMN):
- Dose: 250-500 mg/day
- Function: Increases NAD+ biosynthesis, improving mitochondrial function, insulin sensitivity1.
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Curcumin:
- Dose: 500-2,000 mg/day (with black pepper extract for better absorption)
- Function: Anti-inflammatory, antioxidant properties2.
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Resveratrol:
- Dose: 200-500 mg/day
- Function: Activates sirtuins, mimicking caloric restriction benefits3.
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Coenzyme Q10 (CoQ10):
- Dose: 100-200 mg/day
- Function: Enhances mitochondrial function, reducing oxidative stress4.
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Omega-3 Fatty Acids (EPA and DHA):
- Dose: 1,000-2,000 mg/day
- Function: Improves cardiovascular health, anti-inflammatory properties5.
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Vitamin D3 (Cholecalciferol):
- Dose: 1,000-2,000 IU/day
- Function: Bone health, immune function6.
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Magnesium:
- Dose: 200-400 mg/day
- Function: Nervous system function, muscle health7.
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Astaxanthin:
- Dose: 4-12 mg/day
- Function: Potent antioxidant, protects skin health8.
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Alpha-Lipoic Acid (ALA):
- Dose: 300-600 mg/day
- Function: Reduces oxidative damage, improves insulin sensitivity9.
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Quercetin:
- Dose: 500-1,000 mg/day
- Function: Antioxidant, anti-inflammatory, senolytic activity10.
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Vitamin C (Ascorbic Acid):
- Dose: 500-1,000 mg/day
- Function: Antioxidant, immune support11.
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Vitamin E (Mixed Tocopherols):
- Dose: 100-400 IU/day
- Function: Antioxidant, cardiovascular health12.
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Zinc:
- Dose: 10-40 mg/day
- Function: Immune support, skin health13.
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Selenium:
- Dose: 100-200 mcg/day
- Function: Antioxidant, thyroid function14.
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L-Theanine:
- Dose: 100-200 mg/day
- Function: Reduces stress, enhances cognitive function15.
These ingredients and their doses are based on clinical studies that have evaluated their effects on human health and longevity. Always consult with a healthcare provider before starting any new supplement regimen.
Footnotes
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Harshani Nadeeshani et al., "Nicotinamide mononucleotide (NMN) as an anti-aging health product - Promises and safety concerns," J Adv Res, 2022. ↩
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Lulu Gao et al., "Antiaging effects of dietary supplements and natural products," Front Pharmacol, 2023. ↩
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Ye Chen et al., "Dietary Supplements and Natural Products: An Update on Their Clinical Effectiveness," Front Genet, 2022. ↩
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Lulu Gao et al., "Antiaging effects of dietary supplements and natural products," Front Pharmacol, 2023. ↩
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David R Thomas, "Vitamins in Aging, Health, and Longevity," PMC2682456, 2024. ↩
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Abdullah Al Mahmud et al., "Clinically proven natural products, vitamins, and mineral in boosting up immunity," Heliyon, 2023. ↩
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Lulu Gao et al., "Antiaging effects of dietary supplements and natural products," Front Pharmacol, 2023. ↩
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Bruce N. Ames, "Prolonging healthy aging: Longevity vitamins and proteins," PNAS, 2018. ↩
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Ye Chen et al., "Dietary Supplements and Natural Products: An Update on Their Clinical Effectiveness," Front Genet, 2022. ↩
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Bruce N. Ames, "Prolonging healthy aging: Longevity vitamins and proteins," PNAS, 2018. ↩
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Abdullah Al Mahmud et al., "Clinically proven natural products, vitamins, and mineral in boosting up immunity," Heliyon, 2023. ↩
-
David R Thomas, "Vitamins in Aging, Health, and Longevity," PMC2682456, 2024. ↩
-
Abdullah Al Mahmud et al., "Clinically proven natural products, vitamins, and mineral in boosting up immunity," Heliyon, 2023. ↩
-
Lulu Gao et al., "Antiaging effects of dietary supplements and natural products," Front Pharmacol, 2023. ↩
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Mónika Fekete, "Improving Cognitive Function with Nutritional Supplements in Aging," PMC10746024, 2023. ↩
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is there any other compounds you would add for longevity?