Nicotinamide riboside (NR) is a form of vitamin B3 and acts as a precursor to nicotinamide adenine dinucleotide (NAD+), a crucial coenzyme involved in various metabolic processes. Increasing NAD+ levels in the body through NR supplementation can potentially support various health benefits¹².

1. Metabolic Health: NR is studied for its potential to aid in metabolic disorders by increasing NAD+ levels, which play vital roles in energy metabolism¹.

2. Neurodegenerative Disorders: NR has shown promise in research as a potential aid for neurodegenerative conditions due to its capacity to replenish NAD+, which is often depleted in such diseases².

3. Cardiovascular Health: There is evidence supporting the use of NR for cardiovascular health, as NAD+ is important for energy production and function in heart cells².

4. Aging and Longevity: NR can contribute to healthy aging and longevity through its ability to maintain cellular health by boosting NAD+ levels¹.

5. Therapeutic Potential: Emerging research is investigating NR's potential as a therapeutic agent against infections, including SARS-CoV-2, due to its role in supporting cellular repair and immune function².

Despite its potential benefits, the bioavailability and long-term safety of NR need further investigation².

Footnotes

1. Andrei Biţă, "Nicotinamide Riboside, a Promising Vitamin B3 Derivative for Healthy Aging and Longevity: Current Research and Perspectives," 2023. ↩ ↩² ↩³

2. Mario Mehmel, "Nicotinamide Riboside—The Current State of Research and Therapeutic Uses," 2020. ↩ ↩² ↩³ ↩⁴ ↩⁵