Here's a look at the supplements you've chosen and their potential benefits for mental and physical health:

1. Vitamin D: This vitamin plays various critical roles, including supporting bone health, immune function, and possibly influencing mood and cognitive function¹. Low levels of Vitamin D have been associated with depression and cognitive impairment.

2. Magnesium Glycinate: Magnesium is essential for nerve and muscle function, blood sugar control, and blood pressure regulation². It may aid in reducing anxiety and depression by supporting neurotransmitter function³.

3. Ginkgo: Often used to enhance cognitive function, Ginkgo biloba may aid in improving memory and focus due to its role in increasing blood flow to the brain⁴.

4. Ginseng: Though specific information on its benefits wasn't retrieved, ginseng is generally considered to aid in boosting energy levels, enhancing cognitive function, and reducing stress.

5. Omega-3: Omega-3 fatty acids are crucial for brain health and have been shown to reduce symptoms of depression and anxiety. They are beneficial for supporting heart health and potentially improving cognitive function.

6. Vitamin B Complex: These vitamins are pivotal for maintaining energy levels, brain function, and cell metabolism⁵. They can help reduce fatigue and improve mental clarity.

7. Vitamin K2: It's beneficial to take Vitamin K2 with Vitamin D, as K2 helps to direct calcium to the bones and teeth, which vitamin D helps absorb, thereby improving bone health⁶.

8. Creatine: While it's well-known for enhancing athletic performance, creatine also has cognitive benefits. It may improve short-term memory and reasoning skills, possibly offering support for brain health during stressful periods.

Regarding the Life Extension Two Per Day Multivitamins, these are generally well-regarded for providing essential nutrients at higher potencies than standard multivitamins. The product could be worth it if you are looking for a comprehensive supplement to fill any dietary gaps, assuming it contains most of the vitamins and minerals you're interested in at beneficial dosages.

Given the supplements you've chosen, it looks like a well-rounded approach focused on boosting both physical and mental health. If you are considering other recommendations, perhaps exploring adaptogens like Rhodiola Rosea for stress management or L-theanine for focus could be beneficial based on your needs. However, always consult a healthcare provider before starting any new supplement regimen, especially if you are dealing with symptoms like depression, anxiety, and cognitive difficulties.