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Exploring Long-term Use and Benefits of L-theanine with Caffeine

A user inquires about the safety and efficacy of using L-theanine daily for stress relief and focus, particularly in combination with caffeine. The discussion covers dosage recommendations, potential side effects, and personal experiences to provide guidance for those considering this supplement regimen.

  • Is L-theanine safe for daily, long-term use?

    Hi everyone,

    I’ve been researching L-theanine as a supplement for stress relief and focus, and I’m considering using it daily. From what I’ve read, it seems to be safe for long-term use at doses between 100–400 mg per day, but I wanted to hear from people who’ve actually used it over time. • Have you been taking L-theanine daily for months or years? • Have you experienced any side effects or benefits that changed over time? • Are there any specific precautions I should know about?

    I’m also curious if it’s okay to take alongside caffeine, as I’ve read they complement each other well.

    Would love to hear your experiences or any insights you might have!

    Thanks in advance !

  • L-theanine is generally considered safe for daily, long-term use, particularly at doses ranging from 100 to 400 mg per day1. Many users report benefits such as stress relief and improved focus, often without significant side effects. Long-term use has not been linked with serious adverse effects, although individual responses can vary.

    As for taking L-theanine with caffeine, studies indicate that this combination can enhance cognitive performance and mood. For example, a study involving 50 mg caffeine and 100 mg L-theanine reported improvements in attention switching tasks and reduced susceptibility to distraction, suggesting that these substances can work well together2.

    However, it’s always a good idea to consult with a healthcare provider before starting any new supplement regimen, especially if you have existing health conditions or are taking other medications.

    Footnotes

    1. Gail N Owen, "The combined effects of L-theanine and caffeine on cognitive performance and mood," PubMed, 2024. ↩

    2. Gail N Owen, "The combined effects of L-theanine and caffeine on cognitive performance and mood," PubMed, 2024. ↩

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