March 2012 Supplement Research Papers

• March 1

  • Effect of Lactobacillus acidophilus KFRI342 on the development of chemically induced precancerous growths in the rat colon.

    • 2012-03-01
    • RCT · n = 45
    • Journal of Medical Microbiology 61(3)
    • • Jin-Hee Chang
      • Y. Shim
      • S. Cha
      • M. Reaney
      • K. Chee

    • PubMed: 22034161
    • DOI: 10.1099/jmm.0.035154-0

    13 Insights on

    • Reduced E. coli Levels
    • Reduced Plasma Triglycerides
    • Reduced Beta-Glucuronidase Activity
    • Reduced Aberrant Crypt Foci
    • Reduced Aberrant Crypt Foci Incidence
    • Reduced Fecal E. coli Populations
    • Reduced β-Glucosidase Enzyme Activity
    • Reduced Aberrant Crypts
    • Reduced Fecal Escherichia coli Count
    • Reduced Incidence of Aberrant Crypts
    • Reduced Incidence of Aberrant Crypts Relative to Aberrant Crypt Foci
    • Reduced Escherichia Coli Levels
    • Reduced Aberrant Crypt Number

    • Low evidence
    • Animal Study
• March 15

  • Lactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-κB signaling in the intestine.

    • 2012-03-15
    • Clinical Trial
    • American Journal of Physiology-Gastrointestinal and Liver Physiology 302(6)
    • • Yuying Liu
      • Nicole Y. Fatheree
      • Nisha Mangalat
      • J. M. Rhoads

    • PubMed: 22207578
    • DOI: 10.1152/ajpgi.00266.2011

    10 Insights on

    • Reduced Pro-Inflammatory Cytokines
    • Reduced Intestinal Inflammation
    • Improved Cell Survival Rates
    • Reduced Risk of Necrotizing Enterocolitis
    • Increased Plasma Anti-inflammatory Cytokine Levels
    • Increased Anti-Inflammatory Cytokine IL-10
    • Reduced Proinflammatory Profile from Cow Milk Formula
    • Reduced Proinflammatory Profile
    • Increased Survival Rate in NEC Model
    • Reduced Intestinal Proinflammatory Cytokine Levels

    • Low evidence
    • Highly Cited
    • Animal Study
• March 20

  • Pro-apoptotic effects of Paecilomyces hepiali, a Cordyceps sinensis extract on human lung adenocarcinoma A549 cells in vitro.

    • 2012-03-20
    • Journal of Cancer Research and Therapeutics 7(4)
    • • Asmitananda Thakur
      • Ren Hui
      • Hongyan Zhang
      • Yang Tian
      • Tian-jun Chen
      • Mingwei Chen

    • PubMed: 22269403
    • DOI: 10.4103/0973-1482.92007

    1 Insight on

    • Induced Apoptosis

    • Low evidence
• Undated – 1 supplement study

  • β-Casein hydrolysate generated by the cell envelope-associated proteinase of Lactobacillus delbrueckii ssp. lactis CRL 581 protects against trinitrobenzene sulfonic acid-induced colitis in mice.

    • 2012-03
    • Clinical Trial
    • Journal of Dairy Science 95(3)
    • • M. B. E. Turbay
      • A. LeBlanc
      • G. Perdigón
      • G. S. D. Giori
      • E. Hebert

    • PubMed: 22365194
    • DOI: 10.3168/jds.2011-4735

    14 Insights on

    • Reduced Mortality Rate
    • Improved Macroscopic Colonic Damage
    • Reduced Beta-Glucuronidase Activity
    • Increased IL-10 Production
    • Reduced Myeloperoxidase Activity
    • Reduced Colonic Oxidative Damage
    • Faster Recovery of Body Weight
    • Reduced Microbial Translocation to the Liver
    • Reduced Interferon-Gamma Production
    • Reduced Microbial Translocation
    • Accelerated Weight Loss Recovery
    • Reduced Colonic Microscopic Damage
    • Reduced Gut IFN-γ Production
    • Increased Interleukin-10 Production in the Gut

    • Low evidence
    • Animal Study