Borage oil intake by overweight young adults: no effect on metabolic rate; beneficial effects on plasma triglyceride and HDL cholesterol readings.
- 2021-10-04
- Food & function 12(19)
- Robert A DiSilvestro
- Susan Olivo Marston
- Autumn Zimmerman
- Elizabeth Joseph
- Carolynn Boeh McCarty
- PubMed: 34606560
- DOI: 10.1039/d1fo01887f
Study Design
- Type
- Randomized Controlled Trial (RCT)
- Population
- overweight young adults with a family history of obesity
- Methods
- 6 weeks treatment with borage oil (880 mg GLA per day) or evening primrose oil (540 mg GLA per day)
- Duration
- 6 weeks
- Funding
- Unclear
- Rigorous Journal
Some research has raised the possibility that gamma linolenic acid (GLA) can increase resting metabolic rate (RMR), which can help with weight control. However, in overweight young adults with a family history of obesity, no effect on RMR was seen after a 6 weeks treatment with borage oil (880 mg GLA per day) or evening primrose oil (540 mg GLA per day). On the other hand, borage oil did lower plasma triglyceride readings and raise HDL cholesterol readings (mean starting values in normal range for triglycerides, borderline low for HDL). No effect was seen for body mass index, plasma total cholesterol, LDL cholesterol, or glucose. Thus, in the type of subjects studied here, borage oil, a source of GLA, did not show promise as a weight control aid, but could help prevent undesirable readings for two blood lipid measures.
Research Insights
No effect was seen for body mass index, plasma total cholesterol, LDL cholesterol, or glucose.
- Effect
- Neutral
- Effect size
- Small
- Dose
- 880 mg GLA per day
raise HDL cholesterol readings
- Effect
- Beneficial
- Effect size
- Small
- Dose
- 880 mg GLA per day
no effect on RMR was seen after a 6 weeks treatment with borage oil (880 mg GLA per day) or evening primrose oil (540 mg GLA per day).
- Effect
- Neutral
- Effect size
- Small
- Dose
- 880 mg GLA per day
No effect was seen for body mass index, plasma total cholesterol, LDL cholesterol, or glucose.
- Effect
- Neutral
- Effect size
- Small
- Dose
- 880 mg GLA per day
No effect was seen for body mass index, plasma total cholesterol, LDL cholesterol, or glucose.
- Effect
- Neutral
- Effect size
- Small
- Dose
- 880 mg GLA per day
No effect was seen for body mass index, plasma total cholesterol, LDL cholesterol, or glucose.
- Effect
- Neutral
- Effect size
- Small
- Dose
- 880 mg GLA per day
borage oil did lower plasma triglyceride readings
- Effect
- Beneficial
- Effect size
- Small
- Dose
- 880 mg GLA per day