Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Pillser
Search
Sign UpLog In

Effect of Cardamom Inhalation Therapy on Intra-and Postoperative Nausea and Vomiting of Mothers Undergoing Spinal Anesthesia for Elective Cesarean Section.

  • 2022-08
  • Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses 37(4)
    • Mahnaz Khatiban
    • Masoumeh Mirzaie
    • Akbar Fazeli
    • Leili Tapak
    • Zahra Khalili

Study Design

Type
Randomized Controlled Trial (RCT)
Population
70 eligible participates equally randomized to the intervention or placebo group; mothers undergoing spinal anesthesia for elective cesarean section
Methods
single-blind, randomized, placebo-controlled clinical trial; participants inhaled through a plastic bag containing distilled gauze pads in normal saline with or without Cardamom essential oil upon the first episode of nausea
Blinding
Single-blind

Purpose

This study aimed to determine the effect of cardamom inhalation on intra and postoperative nausea and vomiting (IONV/PONV) of mothers undergoing spinal anesthesia for elective cesarean section.

Design

A single-blind, randomized, placebo-controlled clinical trial study.

Methods

Seventy eligible participates were equally randomized to the intervention or placebo group. The demographic and clinical characteristics questionnaire, a 100 mm Visual Analogue Scale (VAS) to measure the severity of nausea; and the mothers' emetic episodes checklist were used. Upon the first episode of nausea, participants inhaled through a plastic bag containing distilled gauze pads in normal saline with or without Cardamom essential oil.

Findings

Following the intervention, nausea severity in placebo (25.28 ± 32.38) and cardamom (13.14 ± 19.96) groups declined (P < .001), however after controlling the initial severity of nausea, the declining extent was more noticeable in the intervention group than in the placebo group. The episodes of nausea (37.1% vs 65.7%, P = .006), and retching (20% vs 45.7%, P = .028) were significantly lower in the intervention group than in the placebo group. Administration of antiemetic medications was lower in the intervention than the placebo group (37.1% vs 65.7%, P = .009).

Conclusions

Cardamom aromatherapy was effective in alleviating mothers' experience of nausea and retching across the cesarean surgical continuum. As such, it can be considered as a palliative treatment for IONV/PONV in Cesarean section surgeries.

Research Insights

  • Cardamom→Reduced Antiemetic Medication Use

    Administration of antiemetic medications was lower in the intervention than the placebo group (37.1% vs 65.7%, P = .009).

    Effect
    Beneficial
    Effect size
    Moderate
  • Cardamom→Reduced Nausea Severity

    Following the intervention, nausea severity in placebo (25.28 ± 32.38) and cardamom (13.14 ± 19.96) groups declined (P < .001), however after controlling the initial severity of nausea, the declining extent was more noticeable in the intervention group than in the placebo group.

    Effect
    Beneficial
    Effect size
    Moderate
  • Cardamom→Reduced Retching

    and retching (20% vs 45.7%, P = .028) were significantly lower in the intervention group than in the placebo group.

    Effect
    Beneficial
    Effect size
    Moderate
  • Cardamom→Reduced Vomiting Frequency

    The episodes of nausea (37.1% vs 65.7%, P = .006)

    Effect
    Beneficial
    Effect size
    Moderate
Back to top