Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Pillser
Search
Sign UpLog In

Effects of berry consumption on cardiometabolic risk factors in patients with metabolic syndrome: a systematic review and meta-analysis of randomised controlled trials.

  • 2025-05-28
  • International journal of food sciences and nutrition 76(5)
    • Mohammad Amin Mohammadi
    • Ali Ebrahimi Dabagh
    • Shirin Hassanizadeh
    • Gholamreza Askari
    • Mohammad Bagherniya
    • Amirhossein Sahebkar

Study Design

Type
Meta-Analysis
Sample size
n = 50
Population
327 intervention and 284 control subjects with MetS
Methods
Systematic review and meta-analysis of 14 trials
Duration
Not explicitly stated for the overall analysis; subgroup analyses used <12 weeks and >12 weeks
Funding
Unclear
The current study explored the effect of berry consumption on metabolic syndrome (MetS) factors. After full screening, 14 trials were selected for final analysis, involving 327 intervention and 284 control subjects with MetS. Berry consumption significantly increased HDL-C (WMD: 1.771 mg/dL, 95% CI: 1.415-2.128) without affecting LDL-C, TC, TG or leptin levels. BMI, waist circumference, systolic and diastolic BP, TNF-α, IL-6, CRP, adiponectin, HbA1C, HOMA-IR, glucose and insulin remained unaffected. The subgroup analysis showed that interventions <12 weeks resulted in a significant increase in HDL-C levels and a significant decrease in serum TG levels. On the other hand, reductions in IL-6 and glucose levels were observed in interventions >12 weeks. It was also shown that CRP and HDL-C improvements were seen only in studies that included more than 50 participants. Berry consumption may improve HDL-C, glucose, IL-6 and CRP, supporting its inclusion in dietary strategies for managing MetS.

Research Insights

Back to top